Largest Medical Device ETFs by Net Assets

The largest Medical Device ETFs

There are 3 US-listed medical device ETFs, with $3.18B in combined net assets.

The largest is iShares U.S. Medical Devices ETF (IHI) at $3.02B, followed by XHE at $151.4M.

Expense ratios run from 0.35% to 0.7% a year (median 0.37%).

The 3 largest

The largest Medical Device ETFs
#	Fund	Net assets	Cost	Yield	YTD	1 yr	3 yr	5 yr
1	IHI iShares U.S. Medical Devices ETF	$3.02B	0.37%	0.48%	-11.9%	-12.2%	+7.5%	-2.9%
2	XHE SPDR S&P Health Care Equipment ETF	$151.4M	0.35%	0.02%	+5.7%	+14.1%	+11.7%	-5.6%
3	MDEV First Trust Indxx Medical Devices ETF	$1.9M	0.7%	0.09%	+4.8%	+4.2%	+10.3%	-3.5%

Returns are total returns with distributions reinvested (3 and 5 years annualized), as of Oct 27, 2026.

Growth of each fund’s value from the start of the range, distributions reinvested. The dashed gray line is the S&P 500 (SPY).

Largest first. Click a heading to sort.

All Medical Device ETFs
Fund	Issuer	Net assets	Cost	Yield	YTD	1 yr	5 yr
IHI iShares U.S. Medical Devices ETF	iShares	$3.02B	0.37%	0.48%	-11.9%	-12.2%	-2.9%
XHE SPDR S&P Health Care Equipment ETF	SPDR (State Street)	$151.4M	0.35%	0.02%	+5.7%	+14.1%	-5.6%
MDEV First Trust Indxx Medical Devices ETF	First Trust	$1.9M	0.7%	0.09%	+4.8%	+4.2%	-3.5%

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