The 10 largest
| # | Fund | 30 days | Net assets | Cost | Yield | YTD | 1 yr | 3 yr | 5 yr |
|---|---|---|---|---|---|---|---|---|---|
| 1 | XLV Health Care Select Sector SPDR Fund | $40.60B | 0.08% | 1.38% | +20.9% | +30.2% | +16.2% | +8.4% | |
| 2 | VHT Vanguard Health Care ETF | $22.04B† | 0.09% | 1.35% | +20.1% | +28.9% | +16.9% | +7.3% | |
| 3 | IXJ iShares Global Healthcare ETF | $3.84B | 0.38% | 1.33% | +13.2% | +19.5% | +13.4% | +6.4% | |
| 4 | IYH iShares U.S. Healthcare ETF | $3.56B | 0.37% | 1.05% | +16.9% | +23.8% | +15.0% | +7.1% | |
| 5 | FHLC Fidelity MSCI Health Care Index ETF | $3.29B | 0.08% | 1.17% | +17.0% | +23.8% | +16.0% | +7.2% | |
| 6 | FXH First Trust Health Care AlphaDEX Fund | $1.05B | 0.61% | 0.55% | +19.2% | +19.7% | +15.1% | +3.1% | |
| 7 | RSPH Invesco S&P 500 Equal Weight Health Care ETF | $766.9M | 0.4% | 0.56% | +24.2% | +28.4% | +16.6% | — | |
| 8 | PINK Simplify Health Care ETF | $358.6M | 0.51% | 0.75% | +9.8% | +21.1% | +20.0% | +9.8% | |
| 9 | PTH Invesco Dorsey Wright Healthcare Momentum ETF | $235.2M | 0.6% | 2.54% | +21.2% | +31.0% | +28.6% | +3.1% | |
| 10 | PSCH Invesco S&P SmallCap Health Care ETF | $183.9M | 0.29% | 0% | +24.3% | +28.0% | +16.4% | -1.1% |
Returns are total returns with distributions reinvested (3 and 5 years annualized), as of Oct 30, 2026.
How the top 5 compare
Growth of each fund’s value from the start of the range, distributions reinvested. The dashed gray line is the S&P 500 (SPY).
All 20 Broad Healthcare ETFs
Largest first. Click a heading to sort.
| Fund | Issuer | Net assets | Cost | Yield | YTD | 1 yr | 5 yr |
|---|---|---|---|---|---|---|---|
| XLV Health Care Select Sector SPDR Fund | SPDR (State Street) | $40.60B | 0.08% | 1.38% | +20.9% | +30.2% | +8.4% |
| VHT Vanguard Health Care ETF | Vanguard | $22.04B† | 0.09% | 1.35% | +20.1% | +28.9% | +7.3% |
| IXJ iShares Global Healthcare ETF | iShares | $3.84B | 0.38% | 1.33% | +13.2% | +19.5% | +6.4% |
| IYH iShares U.S. Healthcare ETF | iShares | $3.56B | 0.37% | 1.05% | +16.9% | +23.8% | +7.1% |
| FHLC Fidelity MSCI Health Care Index ETF | Fidelity | $3.29B | 0.08% | 1.17% | +17.0% | +23.8% | +7.2% |
| FXH First Trust Health Care AlphaDEX Fund | First Trust | $1.05B | 0.61% | 0.55% | +19.2% | +19.7% | +3.1% |
| RSPH Invesco S&P 500 Equal Weight Health Care ETF | Invesco | $766.9M | 0.4% | 0.56% | +24.2% | +28.4% | — |
| PINK Simplify Health Care ETF | Simplify | $358.6M | 0.51% | 0.75% | +9.8% | +21.1% | +9.8% |
| PTH Invesco Dorsey Wright Healthcare Momentum ETF | Invesco | $235.2M | 0.6% | 2.54% | +21.2% | +31.0% | +3.1% |
| PSCH Invesco S&P SmallCap Health Care ETF | Invesco | $183.9M | 0.29% | 0% | +24.3% | +28.0% | -1.1% |
| CURE Direxion Daily Healthcare Bull 3x Shares Leveraged | Direxion | $171.7M | 0.94% | 0.83% | +38.6% | +61.4% | +6.7% |
| RXL ProShares Ultra Health Care Leveraged | ProShares | $95.6M | 0.95% | 0.96% | +28.4% | +42.7% | +6.6% |
| KURE KraneShares MSCI All China Health Care Index ETF | KraneShares | $71.2M | 0.65% | 4.02% | +3.7% | -5.7% | -9.4% |
| HTEC ROBO Global Healthcare Technology and Innovation … | Exchange Traded Concepts | $69.1M | 0.68% | 0.77% | +28.0% | +36.8% | -0.2% |
| MEDI Harbor Health Care ETF | Harbor | $41.2M | 0.8% | 0.47% | +7.8% | +12.6% | — |
| GDOC Future Health Care Equity ETF | Goldman Sachs | $19.6M | 0.75% | 0.29% | +6.7% | +9.7% | — |
| MEDX Horizon Kinetics Medical ETF | Horizon Kinetics Holding Corp. | $19.1M | 0.85% | 1.11% | +11.1% | +19.1% | — |
| JDOC JPMorgan Healthcare Leaders ETF | JPMorgan | $9.1M | 0.65% | 0.8% | +10.4% | +15.7% | — |
| IBRN iShares Neuroscience and Healthcare ETF | iShares | $5.5M | 0.47% | 0.99% | -0.2% | +7.9% | — |
| RXD ProShares UltraShort Health Care Inverse | ProShares | $2.9M | 0.95% | 2.74% | -26.2% | -34.6% | -12.0% |
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